NCT07185646

Mechanistic Study of SPARC-Mediated Regulation of Neutrophil Extracellular Trap Formation in the Brain Metastatic Microenvironment of Breast Cancer

The Second Xiangya Hospital of Central South University

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Second Xiangya Hospital of Central South University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The objective of this observational study is to investigate the characteristics of the tumor microenvironment in patients with brain tumors using multi-modal magnetic resonance imaging (MRI). The primary research question it aims to address is: • Can multi-modal MRI effectively characterize features of the immune microenvironment in brain tumor patients? Participants: Eligible participants who have been diagnosed with a brain tumor will undergo multi-modal MRI scans for detailed assessment of tumor microenvironment features.

Conditions

• Neuro-Oncology
• MRI Imaging
• Tumor Immune Microenvironment

Timeline

• Start date: 2023-01-01
• Primary completion: 2028-12-30
• Completion: 2030-12-30
• First posted: 2025-09-22
• Last updated: 2025-09-23

Locations

1 site across 1 country: China