NCT07185529

Predictors of Mortality in Multiple Trauma Patients

Predictors of Mortality in Multiple Trauma Patients With Intensive Care Unit: A Retrospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 269 (actual)
• Sponsor: Melike Cengiz · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Trauma is a public health concern that causes serious financial and medical burdens worldwide. According to the World Health Organization, 4.4 million people die from traumatic injuries each year which account for about 8% of global deaths. Traumatic injuries are among the most common causes of mortality particularly in young individuals. It also has a negative economic impact due to the loss of labor. Determining the factors associated with mortality in the ICU follow-up and treatment of these patients is very important for clarifying these uncertainties and improving ICU outcomes. The main objective of the study was to ascertain the ICU processes of multipletrauma patients and the factors that may have an effect on mortality.

Detailed description

All patients with traumatic injuries severe enough to warrant ICU admission formed the subjects of the study. The study included patients aged 18 years and over who were diagnosed with multiple trauma injuries and admitted to the ICU.The analysis included patients with a final outcome (survival or death) at our centre. Only patients who were admitted to the ICU for the first time were included. The following systems were used to assess the clinical and multiple trauma injury severity at the time of admission to the ICU: the Acute Physiology and Chronic Health Assessment II (APACHE II) score, the Simplified Acute Physiology Score II (SAPS II), the Sequential Organ Failure Assessment (SOFA) score, the Glasgow Coma Scale (GCS), the Injury Severity Score (ISS), the Revised Trauma Score (RTS) and the Trauma and Injury Severity Score (TRISS). All injury severity scores were calculated using clinical findings, imaging results and surgical findings. A comprehensive data set was collated at the time of admission to the intensive care unit, encompassing patient age, gender, comorbidities, and the Charlson Comorbidity Index (CCI). The injury mechanism, blood sugar, haemoglobin and lactate levels, Horowitz index, hypotension and hypothermia were also recorded.The patients were categorised into two groups: survival and mortality

Conditions

• Multiple Trauma/Injuries

Interventions

Type	Name	Description
OTHER	Data of the patients were obtained from patient observation files and hospital information system database.	Data of the patients were obtained from patient observation files and hospital information system database.

Timeline

• Start date: 2021-01-01
• Primary completion: 2023-11-01
• Completion: 2025-07-15
• First posted: 2025-09-22
• Last updated: 2025-09-22

Locations

1 site across 1 country: Turkey (Türkiye)