NCT07178626

Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients

Association of Biomarkers and Gastric Antral Motility Index With Feeding Intolerance in Critically Ill Patients: the BGM-FI Study

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 160 (estimated)
• Sponsor: The First Hospital of Jilin University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

When the subjects are admitted to the department, the researchers will monitor potential biomarkers of gastrointestinal injury before administering enteral nutrition (a small amount of blood is drawn, serum is separated by centrifugation, and the serum sample is frozen for final centralized biomarker detection), and measure the antral movement index under ultrasound (300ml of warm water is injected into the stomach before measurement, and then the antral movement is observed for 6 minutes) Then, monitor whether the patient has developed feeding intolerance within 7 days of the ICU

Conditions

• Critically Ill Patients Who Are Not Allowed to Eat Orally But Can Initiate Enteral Nutrition Within 48 Hours of ICU

Interventions

Type	Name	Description
OTHER	Not applicable- observational study	This is a prospective observational study and does not involve any intervention measures

Timeline

• Start date: 2025-10-20
• Primary completion: 2026-07-31
• Completion: 2026-12-31
• First posted: 2025-09-17
• Last updated: 2026-01-02

Locations

1 site across 1 country: China