NCT07177378

Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap Closure

Management of Medication Related Osteonecrosis of the Jaws Using Piezosurgery With Simultaneous Double Periosteal Flap Closure

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

20 patients with MRONJ underwent surgical debridement using piezosurgery then closure using double periosteal flap

Detailed description

20 patients with MRONJ underwent surgical debridement, crestal incision and oblique releasing incision were performed to expose the area of osteomyelitis, then squesterum was removed using piezosurgery. After complete debridement, the periosteal layer was dissected from mucoperiosteal buccal flap and based superiorly, then turn upward to be sutured to the lingual flap followed by suturing of buccal flap to achieve double layers closure

Conditions

• Osteomyelitis of Jaw

Interventions

Type	Name	Description
DEVICE	management of medication related osteonecrosis of the jaw	after buccal flap reflection, the bone osteonecrosis was debrided using piezosurgery. the buccal mucoperiosteal flap was dissected to two layers first, the periosteal layer was based superiorly and the mucosal flap to achieve double layers closure.

Timeline

• Start date: 2025-01-03
• Primary completion: 2026-11-18
• Completion: 2026-12-26
• First posted: 2025-09-17
• Last updated: 2025-09-17

Locations

1 site across 1 country: Egypt