NCT07176000

Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

Strengthening Awareness and Community Resources for Early Detection of Lung Cancer Through Navigation Guided Screening Trial (SACRED LUNGS Aims 1.2-3)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 237 (estimated)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This clinical trial studies whether tailored patient navigation (PN) works to improve the uptake of lung cancer screening (LCS) in tribal communities in western Washington state. Lung cancer is the leading cause of cancer death in the United States among American Indian (AI) and Alaska Native (AN) people, and the incidence of lung cancer is higher in this population in the Northern and Southern Plains, Alaska, and Pacific Coast regions. In Washington state, AI/AN people also have twice the rate of commercial cigarette smoking than the overall population. LCS with annual low-dose chest computed tomography (CT) can reduce lung cancer death and is recommended in people 50-80 years of age with current or recent (within 15 years) tobacco use and a 20 pack-year or greater smoking history. Despite this, AI and AN people are less likely to receive LCS which may be due to barriers they face making it difficult to receive LCS. PN services are designed to guide a patient through the healthcare system and reduce barriers to timely screening, follow-up, diagnosis, treatment, and supportive care. The PN services in this trial have been tailored for the tribal communities in western Washington state. The services are designed to help participants overcome the unique barriers that their tribal communities face and improve the uptake of LCS.

Detailed description

OUTLINE: Participants are randomized to 1 of 2 arms. ARM 1: Participants receive tailored PN activities in support of the uptake and follow-up of LCS for 21 months. Participants also receive an educational handout on LCS on study. ARM 2: Participants receive enhanced usual care consisting of an educational handout on LCS and a warm hand-off to discuss LCS with their primary care physician (PCP) for 6 months. Participants then receive tailored PN services in support of the uptake and follow-up of LCS for 15 months.

Conditions

• Lung Carcinoma

Interventions

Type	Name	Description
BEHAVIORAL	Patient Navigation	Receive tailored PN activities
OTHER	Educational Intervention	Receive LCS educational handout
OTHER	Best Practice	Receive enhanced usual care
OTHER	Interview	Ancillary studies
OTHER	Survey Administration	Ancillary studies
OTHER	Electronic Health Record Review	Ancillary studies

Timeline

• Start date: 2026-06-01
• Primary completion: 2029-03-29
• Completion: 2029-04-30
• First posted: 2025-09-16
• Last updated: 2026-04-08

Locations

2 sites across 1 country: United States