NCT07174011

Evaluation of the Efficacy and Safety of Oral Roflumilast Versus Intralesional Corticosteroids Injection (ILCs) in the Treatment of Alopecia Areata

Evaluation of the Efficacy and Safety of Oral Roflumilast Versus Intralesional Corticosteroids Injection (ILCs) in the Treatment of Alopecia Areata: A Randomized Controlled Trial.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Weeks
• Healthy volunteers: Not accepted

Summary

Evaluation of the Efficacy and Safety of a drug called Oral Roflumilast versus Intralesional Corticosteroids Injection (ILCs) in the Treatment of Alopecia Areata.

Detailed description

we are going to evaluate using oral immunomodulator called Roflumilast and compare its safety and efficacy to intralesional steroid injection in the treatment of Alopecia areata

Conditions

• Alopecia
• Alopecia Areata

Interventions

Type	Name	Description
DRUG	Roflumilast	Phosphodiesterase-4 (PDE4) inhibitor assigned to arm A
DRUG	intralesional steroid	intralesional injection of corticosteroid

Timeline

• Start date: 2025-01-12
• Primary completion: 2025-05-20
• Completion: 2025-08-20
• First posted: 2025-09-15
• Last updated: 2025-09-15

Locations

1 site across 1 country: Egypt