Trials / Recruiting
RecruitingNCT07173868
FDG PET-CT in Advanced Breast Cancer
A Prospective Cohort Study Comparing Metabolic Response Evaluation by F-18 FDG PET-CT Versus Conventional Imaging for Outcome Stratification in Patients With Advanced Breast Cancer Receiving First-line Systemic Therapy
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Samsung Medical Center · Academic / Other
- Sex
- All
- Age
- 19 Years
- Healthy volunteers
- Not accepted
Summary
This study is a prospective cohort study comparing metabolic response evaluation by F-18 FDG PET-CT versus conventional imaging for outcome stratification in patients with advanced breast cancer receiving first-line systemic therapy.
Detailed description
PET-CT, CE-CT ± bone scan are performed before and during treatment (6, 12, 24, 48 weeks) of the first systemic treatment in a total of 100 patients with advanced breast cancer, and some patients analyze ctDNA-based MRD by collecting blood at the same time point. We analyze the relationship between patient-specific responses and PFS, and compare the predictive performance of imaging and molecular indicators.
Conditions
- Histologically Confirmed Metastatic or Locally Advanced Breast Cancer With no Radical Topical Treatment Available
- If There is Liver Metastasis, Which the Researcher Believes Will be Difficult to Evaluate the Response Accurately With Bone Metastasis or CT
Timeline
- Start date
- 2025-07-25
- Primary completion
- 2025-12-30
- Completion
- 2027-12-31
- First posted
- 2025-09-15
- Last updated
- 2025-09-15
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT07173868. Inclusion in this directory is not an endorsement.