NCT07169695

A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis

Efficacy and Safety Assessment of T1695 Ophthalmic Suspension, Versus Ciclosporin Ophthalmic Emulsion, in Participants With Moderate to Severe Vernal Keratoconjunctivitis (VKC)

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Laboratoires Thea · Industry
• Sex: All
• Age: 4 Years – 17 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants with Moderate to Severe Vernal Keratoconjunctivitis

Conditions

• Moderate to Severe Vernal Keratoconjunctivitis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Slit Lamp Examination	The participant will have a slit lamp examination
DIAGNOSTIC_TEST	Far Best Corrected Visual Acuity (BCVA)	The participant 's BCVA will be evaluated.
DRUG	T1695	The participant should instill T1695.
DRUG	Ciclosporin	The participant should instill Ciclosporin.
DIAGNOSTIC_TEST	Corneal fluorescein staining score on modified Oxford scale	One drop of fluorescein will be instilled to assess the fluorescein staining score on the modified Oxford scale.

Timeline

• Start date: 2026-03-24
• Primary completion: 2027-01-21
• Completion: 2027-01-21
• First posted: 2025-09-12
• Last updated: 2026-04-15

Locations

11 sites across 1 country: India