NCT07164898

How Wet Pads Affect Elderly Skin: Measuring Changes in the Skin Barrier

Impact to Skin Due to Wet Pad Application. Skin Status and Change in the Stratum Corneum as Measured With 4 Instruments in an Elderly Population.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Essity Hygiene and Health AB · Industry
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The main aim of this study is to describe the effects of dry or wet incontinence pad material on the skin barrier function by measuring the changes of the stratum corneum on healthy participants due to the application of pads with varying wetness level to the forearm. Study findings have relevance for product development of absorbing incontinence products to further protect the skin from the damaging effects of excess moisture. Participants are subject to baseline measures of TEWL, SH, pH and water profile. Dry or wet pads are then added to the forearm skin and worn for two hours. After a recovery period, the SSWL, SH and water profile is measured. The study is conducted over a single 4h visit. As this is an explorative study no hypothesis is intended to be tested.

Conditions

• Incontinence-associated Dermatitis

Interventions

Type	Name	Description
DEVICE	Test patches	Patches (incontinence product cut outs) either dry, 50% saturated with water or 100% saturated with water applied to the forearm and worn for 2 hours

Timeline

• Start date: 2023-12-13
• Primary completion: 2024-02-09
• Completion: 2024-04-30
• First posted: 2025-09-10
• Last updated: 2025-09-10

Locations

1 site across 1 country: Sweden