NCT07162454

Effectiveness of CBD for Neuropathic Pain in Diabetic Foot Neuropathy

A Triple-Blind Randomised Clinical Trial on the Effectiveness of CBD for Neuropathic Pain in Diabetic Foot Neuropathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Universidad Complutense de Madrid · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Evaluation of cannabidiol and urea 10%.

Detailed description

This study evaluated the impact of cannabidiol on neuropathic pain and the action of urea 10% on skin quality in patients with diabetic foot syndrome and diabetic neuropathy.

Conditions

• Xerosis Cutis
• Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Interventions

Type	Name	Description
DRUG	Group 1. Complete formula	After fulfilling the criteria and agreeing to participate in the study, patients who were included in group 1 after randomisation were evaluated and received a topical cream with cannabidiol, Urea 10%, arnica and menthol as active ingredients. After one month of application of the formula, a second evaluation was carried out.
DRUG	Group 2. Cannabidiol and Urea 10% formula.	After meeting the criteria and agreeing to participate in the study, the patients who were included in group 2 after randomisation were evaluated and received a topical cream containing cannabidiol and 10% urea. After one month of application of the formula, a second evaluation was carried out.
DRUG	Group 3. Placebo formula.	Participants included in this group after randomisation received a formulation with no active ingredients included in its composition and were assessed at baseline and after one month.

Timeline

• Start date: 2024-11-01
• Primary completion: 2025-05-31
• Completion: 2025-06-30
• First posted: 2025-09-09
• Last updated: 2025-10-01

Locations

1 site across 1 country: Spain