NCT07161713

SBU-RESET: RElaxation, Stress Reduction and Epigenetics Trial in Cancer Survivors

Pilot Study of a Social/Behavioral Intervention on Lung, Colon, and Non-Hodgkin's Lymphoma (NHL) Cancer Survivors, Evaluating the Effect of Mind Body Interventions on Patient Reported Outcomes, Inflammation and Epigenetics.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Barbara Nemesure · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cancer survivors can experience health issues that cause chronic illness and lower quality of life. Yoga is a well-known holistic approach to health and overall well-being. Mindfulness has many benefits, including improved focus and less stress. This study aims to evaluate if yoga and/or mindfulness has a positive effect on cancer survivors social, emotional and physical well-being as well as their epigenetics. Epigenetics is how the environment can effect your genes; not by changing our DNA, but by turning genes on or off.

Detailed description

Randomized interventional pilot study to evaluate whether a mind-body intervention (Stress Management and Resiliency Training (SMART) or (oncology-informed yoga) influences patient-reported Quality of life (QoL) outcomes (physical/social/emotional/ functional well-being and symptom burden) in Lung Colon, and Non-Hodgkin's lymphoma (NHL) survivors. A secondary (exploratory) aim is to evaluate whether these mind-body interventions impact epigenetics.

Conditions

• Lung Adenocarcinoma
• Lung Adenocarcinoma Metastatic
• Lung Adenocarcinoma Stage III
• Lung Adenocarcinoma Stage IIIB/IV
• Lung Adenocarcinoma Stage IV
• Lung Adenocarcinoma Stage I
• Lung Adenocarcinoma Stage II
• NHL
• NHL - Non-Hodgkin&Amp;#39;s Lymphoma
• Lung Cancer (Diagnosis)
• Colon Cancer

Interventions

Type	Name	Description
BEHAVIORAL	Oncology-informed yoga	8 weekly sessions of cancer informed-yoga incorporating light movement, breathing techniques, and some meditation practices
BEHAVIORAL	SMART	SMART, developed by the Impact Foundation, is an adaptation of Mindfulness-based Stress Reduction (MBSR) approach that incorporates other elements like mindful self-compassion, emotional literacy, and positive psychology principles to address the unique stressors faced by teachers.

Timeline

• Start date: 2025-09-17
• Primary completion: 2027-09-17
• Completion: 2027-09-30
• First posted: 2025-09-09
• Last updated: 2025-09-23

Locations

1 site across 1 country: United States