NCT07159789

Repetitive Transcranial Magnetic Stimulation (rTMS) in MS Induced Spastic Paraparesis

Non-Invasive Neuromodulation in MS Induced Spastic Paraparesis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Clinique Neuro-Outaouais · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Study the impact of rTMS on walking ability in people with Multiple Sclerosis (MS) induced spastic paraparesis and moderate walking disability.

Detailed description

Measure the impact of rTMS on overall disability level, walking endurance, quality of life parameters, and corroborate with EEG parameters of neural synchrony in patients with MS.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
DEVICE	Repetitive Transcranial Magnetic Stimulation	Treatment with the rTMS or sham rTMS will be scheduled daily 5x per week for a total of 6 consecutive weeks followed, after a 6 week pause, by another treatment session of 6 weeks where all patients will receive active rTMS treatment

Timeline

• Start date: 2025-10-15
• Primary completion: 2027-10-01
• Completion: 2028-03-01
• First posted: 2025-09-08
• Last updated: 2025-12-04

Locations

1 site across 1 country: Canada