NCT07158177

Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity

Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity. Study of Two Different Material of Intra Ocular Multifocal Lenses Aiming to Compare the Effect on Contrast Sensitivity.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Retrospective, comparative, interventional, randomized, single-center study, contralateral (the patient's 2 eyes will be implanted: 1 CPO and the other APO) Patients presenting for cataract surgery with a request for presbyopia correction and managed as part of routine clinical practice. The main aim of the study is to demonstrate that contrast sensitivity is better with the Clareon PanOptix (CPO) intraocular lens (IOL) compared with the AcrySof PanOptix (APO) IOL 3 months after implantation.

Detailed description

Visit at Day3-10: usual follow-up visit, no additional examinations as part of the clinical investigation. Visit at 1 month: usual follow-up visit, no additional examinations as part of the clinical investigation. 3-month visit (end of clinical investigation): usual follow-up visit, plus contrast vision test and non-invasive aberrometry test (I-Trace) as part of the clinical investigation. Regarding a cataract surgery with a request for presbyopia, the protocol evaluate two differents devices (IOL intraocular lens).

Conditions

• Cataract and IOL Surgery

Interventions

Type	Name	Description
DEVICE	Acrysof™ PanOptix™ toric or not, trifocal IOL CE marked, Alcon company.	both of the patient's eyes will be implanted: 1 CPO and the other APO
DEVICE	Clareon Panoptix	both of the patient's eyes will be implanted: 1 CPO and the other APO

Timeline

• Start date: 2025-10-01
• Primary completion: 2026-10-15
• Completion: 2026-10-15
• First posted: 2025-09-05
• Last updated: 2026-03-30

Locations

1 site across 1 country: France