NCT07155018

Micro-Osteoperforations to Accelerate Maxillary Canine Retraction in Class I Malocclusion

Effectiveness of Micro-Osteoperforations (MOPs) in Accelerating Maxillary Canine Retraction in Angle Class I Malocclusion: A Randomized Controlled Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Can Tho University of Medicine and Pharmacy · Academic / Other
• Sex: All
• Age: 16 Years – 25 Years
• Healthy volunteers: Accepted

Summary

This single-blinded, split-mouth randomized controlled trial investigates whether micro-osteoperforations (MOPs) can accelerate maxillary canine retraction in orthodontic patients requiring bilateral premolar extraction. The study also evaluates postoperative pain levels using the Visual Analog Scale at 1, 3, and 7 days.

Detailed description

MOPs are a flapless, minimally invasive surgical technique that stimulates bone remodeling and may reduce orthodontic treatment time. In this trial, one side of each patient receives MOPs while the contralateral side serves as control. Canine retraction is performed using miniscrews, power arms, and NiTi coil springs. Outcomes include the rate of canine movement over 16 weeks and pain assessment using VAS.

Conditions

• Malocclusion, Angle Class I

Interventions

Type	Name	Description
PROCEDURE	Micro-osteoperforations (MOPs)	Maxillary canine retraction with miniscrew anchorage and NiTi closed-coil springs, without micro-osteoperforations.
PROCEDURE	Conventional Canine Retraction	Maxillary canine retraction with miniscrew anchorage and NiTi closed-coil springs, without micro-osteoperforations

Timeline

• Start date: 2025-01-01
• Primary completion: 2025-04-30
• Completion: 2025-06-30
• First posted: 2025-09-04
• Last updated: 2025-09-04

Locations

1 site across 1 country: Vietnam