NCT07152470

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss in a Real World Setting.

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Prostasis, LLC, dba Tonum Health · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

The goal of this clinical trial is to learn if motus, a natural supplement can support healthy weight loss and fat loss in a real world setting without caloric restrictions or exercise requirements. The main questions it aims to answer are: Can a daily dose of motus result in statistically significant weight loss over 3 month and 6 month time points. Participants will: Weigh-in at baseline and every week thereafter Take drug motus every day Complete a food tracker app for every meal and drink product consumed daily Complete an exercise tracker for any activities performed daily Complete weekly satisfaction surveys on various topics

Detailed description

A prospective, observational human study was conducted with 100 participants (ages 25-68, BMI ≥25) over an initial 12-week period, followed by a 12-week extension phase for 40 continuing participants. All subjects received motus (4-capsule daily dose) and were instructed to track food intake and exercise via food tracker app and digital fat measurement scales. No caloric restriction was mandated, and participants could optionally receive nutritional counseling. Weekly weigh-ins and quality of life surveys were completed. No financial compensation was provided. Participants were stratified post hoc into three behavioral groups based on food and activity logs reviewed by registered dietitians: Category 1 (healthy diet + exercise 4+ times per week), Category 2 (average diet + exercise 2-3 times per week), Category 3 (average diet + no exercise) and Category 4 (poor diet + no exercise).

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
BEHAVIORAL	Diet and Exercise Tracking	To determine if diet and/or exercise had any impact on weight loss while taking motus.

Timeline

• Start date: 2025-01-26
• Primary completion: 2025-07-26
• Completion: 2025-12-26
• First posted: 2025-09-03
• Last updated: 2025-09-09

Locations

1 site across 1 country: United States