NCT07148973

Outcomes for Patients With Ascending Aortic Dilation Who Underwent TAVR

Outcomes for Patients With Ascending Aortic Dilation Who Underwent Transcatheter Aortic Valve Replacement in a Chinese Population

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 101 (actual)
• Sponsor: zjq · Academic / Other
• Sex: All
• Age: 50 Years – 93 Years
• Healthy volunteers: Not accepted

Summary

The present study was designed to evaluate the safety of TAVR with a preoperative ascending aortic (AA) diameter ≥ 40 mm. This study also aimed to explore the procedural outcomes and clinical prognoses of patients with AAD combined compared to those of patients without AAD combined who underwent TAVR. Between January 2019 and July 2021, a total of 186 patients who were diagnosed at a single centre with severe AS underwent the TAVR procedure using a self-expanding valve. The AA diameter was evaluated via 3-dimensional (3D) multidetector computed tomography (MDCT) before TAVR. AAD was defined as a value of AAD ≥ 40 mm.

Conditions

• Transcatheter Aortic Valve Replacement (TAVR)
• Ascending Aortic Dilation

Interventions

Type	Name	Description
PROCEDURE	Transcatheter Aortic Valve Replacement	The TAVR surgery mainly involves attaching an artificially-made aortic valve to a special catheter, and then using the catheter to deliver the valve to the affected area and release it. This surgery replaces the original aortic valve with an artificial one, thereby restoring the valve function. Compared with traditional open-chest surgery, it causes less trauma, has lower risks, and enables faster recovery. It is particularly suitable for patients who cannot tolerate open-chest surgery, have poor cardiac function, or are older.

Timeline

• Start date: 2019-01-01
• Primary completion: 2021-07-31
• Completion: 2021-07-31
• First posted: 2025-08-29
• Last updated: 2025-10-08

Locations

1 site across 1 country: China