NCT07148687

ChatGPT and DeepSeek-Assisted Rehabilitation in Subacromial Pain

Effect of ChatGPT and DeepSeek-Guided Rehabilitation on Clinical Outcomes in Individuals With Subacromial Pain Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (actual)
• Sponsor: Kirsehir Ahi Evran Universitesi · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the effects of rehabilitation programs supported by artificial intelligence-based large language models (LLMs), specifically ChatGPT and DeepSeek, in individuals with subacromial pain syndrome (SAPS). Participants will be randomly assigned to one of three groups: standard physiotherapy, standard physiotherapy plus ChatGPT-guided exercises, and standard physiotherapy plus DeepSeek-guided exercises. Outcomes including pain, disability, quality of life, muscle strength, and joint range of motion will be assessed before and after a 6-week intervention. The results will help determine whether AI-generated exercise recommendations can enhance clinical outcomes when combined with conventional physiotherapy.

Detailed description

This completed randomized controlled trial investigated the clinical effects of integrating AI-generated exercise recommendations into conventional physiotherapy for individuals with subacromial pain syndrome (SAPS). A total of 82 individuals were assessed for eligibility; 7 were excluded for not meeting inclusion criteria. Seventy-five participants provided consent and were randomized in a 1:1:1 ratio to 3 groups (n=25 each): (1) conventional physiotherapy plus a conventional exercise program, (2) conventional physiotherapy plus ChatGPT-guided exercises, and (3) conventional physiotherapy plus DeepSeek-guided exercises. The allocation sequence was generated using simple computer-based randomization by an independent staff member and was revealed after completion of baseline assessments. Interventions were delivered over 6 weeks (3 supervised sessions/week). Six participants discontinued the intervention due to scheduling conflicts (2 per group). Sixty-nine participants completed the 6-week intervention and were included in the final analysis (n=23 per group). The primary outcome was shoulder pain and disability (Shoulder Pain and Disability Index, SPADI), assessed at baseline and 6 weeks. Secondary outcomes included pain intensity (Numeric Pain Rating Scale, NPRS), health-related quality of life (Short Form-12, SF-12), upper limb function (Disabilities of the Arm, Shoulder and Hand, Quick DASH), range of motion, isometric strength, kinesiophobia, catastrophizing, emotional status, and disease-specific quality of life.

Conditions

• Subacromial Pain Syndrome

Interventions

Type	Name	Description
BEHAVIORAL	Conventional Exercise Program	Exercise protocol targeting subacromial pain syndrome, including shoulder mobility, strengthening, and posture correction exercises based on established clinical guidelines.
BEHAVIORAL	ChatGPT-Guided Rehabilitation	AI-generated exercise recommendations from ChatGPT-4 tailored to the patient's profile and applied under physiotherapist supervision.
BEHAVIORAL	DeepSeek-Guided Rehabilitation	Personalized rehabilitation exercises generated by DeepSeek-R1 and implemented under physiotherapist guidance.

Timeline

• Start date: 2025-09-25
• Primary completion: 2025-12-01
• Completion: 2025-12-20
• First posted: 2025-08-29
• Last updated: 2026-02-27

Locations

1 site across 1 country: Turkey (Türkiye)