NCT07143669

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

A Multicenter Screening Study to Characterize the Prevalence of the KIT D816V Mutation in Patients With Suspected Clonal Mast Cell Disease

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 450 (estimated)
• Sponsor: Blueprint Medicines Corporation · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a multicenter screening study to characterize the prevalence of the KIT D816V mutation in participants with suspected clonal mast cell disease.

Conditions

• Clonal Mast Cell Disease
• KIT D816V Mutation
• Suspected KITD816V Mutated Clonal Mast Cell Disease

Interventions

Type	Name	Description
OTHER	Screening	After providing informed consent and relevant medical history data, samples will be collected from participants with suspected clonal mast cell disease.

Timeline

• Start date: 2025-10-17
• Primary completion: 2028-07-31
• Completion: 2028-10-31
• First posted: 2025-08-27
• Last updated: 2026-03-31

Locations

16 sites across 1 country: United States