Trials / Active Not Recruiting
Active Not RecruitingNCT07143656
Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
Natural History and Biomarker Correlation Study in Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 36 (actual)
- Sponsor
- Biocells Medical · Industry
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
This retrospective observational study will analyze de-identified clinical data from patients with amyotrophic lateral sclerosis (ALS) collected at multiple centers over 7 years. The primary objective is to describe disease progression using the ALS Functional Rating Scale-Revised (ALSFRS-R). Secondary objectives include evaluating survival, ventilatory decline, and correlations between available biomarkers (e.g., neurofilament light chain, cytokines) and disease trajectory. No new interventions or patient contact will occur.
Conditions
- Amyotrophic Lateral Sclerosis (ALS)
- Amyotrophic Lateral Sclerosis &Amp; Other Neuromuscular Disorders
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Imaging and Clinical Reports | Inclusion of existing imaging data (MRI, EMG reports) and standard clinical documentation, where available. |
Timeline
- Start date
- 2021-05-13
- Primary completion
- 2028-08-13
- Completion
- 2028-09-01
- First posted
- 2025-08-27
- Last updated
- 2025-08-28
Locations
1 site across 1 country: Poland
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT07143656. Inclusion in this directory is not an endorsement.