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Active Not RecruitingNCT07143227

A Study of XW003 Injection in Chinese Adolescents With Obesity

A Randomized, Double-blind, Placebo-controlled Phase Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Dosing of XW003 Injection in Chinese Adolescents With Obesity

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
48 (actual)
Sponsor
Hangzhou Sciwind Biosciences Co., Ltd. · Industry
Sex
All
Age
12 Years – 18 Years
Healthy volunteers
Accepted

Summary

The aim of the study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of XW003 injection in Chinese adolescents with obesity

Detailed description

In this study, eligible participants will be randomized into one of the three cohorts in a 3:1 ratio to receive either once-weekly subcutaneous XW003 injection or placebo, for up to 20 weeks.

Conditions

Interventions

TypeNameDescription
DRUGXW003 injectionSubcutaneous injection
DRUGplacebo with matching volumeSubcutaneous injection

Timeline

Start date
2025-08-25
Primary completion
2026-06-30
Completion
2026-12-31
First posted
2025-08-27
Last updated
2026-04-13

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07143227. Inclusion in this directory is not an endorsement.

A Study of XW003 Injection in Chinese Adolescents With Obesity (NCT07143227) · Clinical Trials Directory