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Active Not RecruitingNCT07142161

A Study on the Safety, Preliminary Efficacy, and Cellular Kinetics of Allo-CD7 CAR-T Cells in T1DM

A Study on the Safety, Preliminary Efficacy, and Cellular Kinetics of Allogeneic CD7-targeted CAR-T Cell Injection in the Treatment of Type 1 Diabetes

Status
Active Not Recruiting
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
3 (estimated)
Sponsor
Nanjing Bioheng Biotech Co., Ltd. · Industry
Sex
All
Age
1 Year – 60 Years
Healthy volunteers
Not accepted

Summary

This is an open clinical pharmacological translational Research Study, aiming to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of RD13-02 in patients with aT1DM

Conditions

Interventions

TypeNameDescription
DRUGRD13-02 cell infusionCAR T-cell therapy administered intravenously after a lymphodepleting therapy regimen consisting of fludarabine and cyclophosphami

Timeline

Start date
2025-07-20
Primary completion
2026-07-24
Completion
2026-12-25
First posted
2025-08-26
Last updated
2025-08-26

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07142161. Inclusion in this directory is not an endorsement.

A Study on the Safety, Preliminary Efficacy, and Cellular Kinetics of Allo-CD7 CAR-T Cells in T1DM (NCT07142161) · Clinical Trials Directory