NCT07141394

Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing

Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing (CARE-VASH) (QUE 25-013)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 7,908 (estimated)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The Department of Housing and Urban Development-VA Supportive Housing (HUD-VASH) Program provides subsidized permanent housing with case management to homeless-experienced Veterans (HEVs). Up to 40% of Veterans exit HUD-VASH within two years of attaining housing; substance use disorders (SUDs) are one of the largest causes of returns to homelessness for HEVs. CARE-VASH QUERI proposes to implement and evaluate two evidence-based SUD services - Medications for addiction treatment (MAT) and cognitive behavioral therapy for SUDs (CBT-SUD) - among Veterans in HUD-VASH.

Detailed description

The Department of Housing and Urban Development-VA Supportive Housing (HUD-VASH) program provides subsidized, permanent housing and supports to Veterans experiencing homelessness. Substance use disorders (SUDs) are a common primary or contributing factor to negative exits from HUD-VASH. The Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing (CARE-VASH) QUERI will implement two evidence-based practices (EBPs) for SUDs-Medications for Addiction Treatment (MAT) and cognitive behavioral therapy for SUDs (CBT-SUD)-in 12 HUD-VASH sites. We will use the Replicating Effective Programs (REP) implementation bundle to support EBP implementation at all 12 sites. Half the sites (n=6) will also receive 9 months of consumer engagement (REP+CE). In a type 3 hybrid trial, we will use mixed methods to examine the impacts of REP vs. REP+CE. Using our trial data, we will develop a budget impact analysis and implementation playbook for our program partners to spread and sustain MAT and CBT-SUD in HUD-VASH.

Conditions

• Homelessness
• Substance Use Disorder (SUD)

Interventions

Type	Name	Description
DRUG	Medication for Addiction Treatment (MAT)	MAT includes medications for alcohol use disorder (MAUD) and medications for opioid use disorder (MAUD). It reduces substance use, increases SUD treatment engagement, enhances quality of life, and reduces overdoses.
BEHAVIORAL	Cognitive Behavioral Therapy for Substance Use Disorders (CBT-SUD)	An evidence-based psychotherapy that uses cognitive behavioral therapy to further recovery goals across SUD diagnoses.

Timeline

• Start date: 2026-10-01
• Primary completion: 2030-09-30
• Completion: 2030-09-30
• First posted: 2025-08-26
• Last updated: 2025-10-10

Locations

1 site across 1 country: United States