Clinical Trials Directory

Trials / Completed

CompletedNCT07139054

68Ga-FAPI-46 PET/CT for the Prediction of Clinical Response to Neoadjuvant Therapy in Nasopharyngeal Carcinoma Patients

68Ga-Labeled Fibroblast Activation Protein Inhibitor PET/CT for the Prediction of Clinical Response to Neoadjuvant Therapy in Nasopharyngeal Carcinoma Patients: A Prospective Study

Status
Completed
Phase
Study type
Observational
Enrollment
31 (actual)
Sponsor
The First Affiliated Hospital of Xiamen University · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers

Summary

The goal of this clinical trial is to learn about the prediction of clinical response to neoadjuvant therapy in nasopharyngeal carcinoma patients via 68Ga-FAPI-46 PET/CT. The main question it aims to answer is: Can 68Ga-FAPI-46 PET/CT be used to evaluate the therapeutic response of neoadjuvant therapy for nasopharyngeal carcinoma? The researchers will compare the correlation between the parameters obtained after three 68Ga-FAPI-46 PET/CT scans and the treatment response after neoadjuvant and neoadjuvant combined with concurrent chemoradiotherapy. Participants will: Undergo three 68Ga-FAPI-46 PET/CT scans before starting treatment, after neoadjuvant therapy, and after concurrent chemoradiotherapy

Conditions

Timeline

Start date
2024-01-31
Primary completion
2025-03-31
Completion
2025-08-10
First posted
2025-08-24
Last updated
2025-08-24

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07139054. Inclusion in this directory is not an endorsement.

68Ga-FAPI-46 PET/CT for the Prediction of Clinical Response to Neoadjuvant Therapy in Nasopharyngeal Carcinoma Patients (NCT07139054) · Clinical Trials Directory