Trials / Recruiting
RecruitingNCT07138794
Ultrasound-Guided Subtransverse Interligamentary Block Versus Thoracic Paravertebral Block for Postoperative Analgesia in Patients Undergoing Open Nephrectomy
Ultrasound-Guided Subtransverse Interligamentary Block Versus Thoracic Paravertebral Block for Postoperative Analgesia in Patients Undergoing Open Nephrectomy: A Randomized Clinical Trial
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- Sponsor
- Tanta University · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to compare ultrasound-guided subtransverse process interligamentary (STIL) block versus thoracic paravertebral block (TPVB) for postoperative analgesia in patients undergoing open nephrectomy.
Detailed description
Acute pain physiopathology is explained as it is mediated by inflammatory cell infiltration, activation of spinal cord pain pathways, and also by reflexive muscle spasm. All of these three mechanisms of acute pain are typically ameliorated during the postoperative recovery. A thoracic paravertebral block (TPVB) shows comparable analgesic efficacy with fewer side effects compared with thoracic epidural analgesia in patients undergoing thoracotomy. The recently introduced subtransverse process interligamentary (STIL) block offers a safer alternative by targeting thoracic nerves without entering paravertebral space.
Conditions
- Subtransverse Interligamentary Block
- Thoracic Paravertebral Block
- Postoperative Analgesia
- Open Nephrectomy
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Subtransverse process interligamentary | Patients will receive subtransverse process interligamentary (STIL) block using 20ml of bupivacaine 0.25%. |
| OTHER | Thoracic paravertebral block | Patients will receive a thoracic paravertebral block (TPVB) using 20ml of bupivacaine 0.25%. |
Timeline
- Start date
- 2025-08-23
- Primary completion
- 2026-02-01
- Completion
- 2026-02-01
- First posted
- 2025-08-24
- Last updated
- 2025-08-26
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT07138794. Inclusion in this directory is not an endorsement.