NCT07138638

High-Frequency QRS for Predicting Microvascular Dysfunction and Adverse Events After PCI in Acute Myocardial Infarction

High-Frequency QRS for Predicting Microvascular Dysfunction and Adverse Events After PCI in Acute Myocardial Infarction: A Prospective, Multicenter Cohort Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,112 (estimated)
• Sponsor: The Affiliated Hospital of Xuzhou Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This observational study aimed to investigate the prognostic value of high-frequency QRS (HF-QRS) in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI), as well as its potential role in diagnosing microvascular dysfunction. The main question it aims to answer is: 1. Whether HF-QRS could serve as an effective tool for early identification of high-risk AMI patients and prognosis prediction; 2. Whether HF-QRS provides auxiliary diagnostic value for post-AMI microvascular dysfunction. Participants underwent HF-QRS assessment and were prospectively followed for 1 year to record the incidence of major adverse cardiovascular events (MACE).

Conditions

• AMI

Interventions

Type	Name	Description
DEVICE	High-Frequency QRS	All enrolled patients underwent HF-QRS assessment, with subsequent recording of MACE to evaluate the predictive value of HF-QRS parameters for clinical outcomes

Timeline

• Start date: 2025-08-01
• Primary completion: 2027-09-01
• Completion: 2027-12-01
• First posted: 2025-08-24
• Last updated: 2025-08-24

Locations

1 site across 1 country: China