NCT07137039

Neoadjuvant Treatment of Locally Advanced Hypopharyngeal Cancer With Adebrelimab Combined With TP Chemotherapy Regimen

A Single-arm, Prospective, Single-center Clinical Study on Neoadjuvant Treatment of Locally Advanced Hypopharyngeal Cancer With Adebrelimab Combined With TP Chemotherapy Regimen

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 34 (estimated)
• Sponsor: The First Affiliated Hospital of Xiamen University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the efficacy and safety of adebrelimab combined with TP chemotherapy regimen as neoadjuvant therapy for locally advanced hypopharyngeal cancer

Conditions

• Locally Advanced Hypopharyngeal Cancer

Interventions

Type	Name	Description
DRUG	Adebrelimab+Albumin paclitaxel +Cisplatin	1. Adebrelimab：1200mg, ivgtt, D1, Q3W; 2. Albumin paclitaxel :260mg/m2, ivgtt, D1, Q3W; 3. Cisplatin :60mg/m2, ivgtt, D1, Q3W.

Timeline

• Start date: 2025-08-20
• Primary completion: 2027-08-20
• Completion: 2028-08-20
• First posted: 2025-08-22
• Last updated: 2025-08-22

Locations

1 site across 1 country: China