NCT07135609

Apitoxin Versus Soft Laser for Management of Aphthous Ulceration.

Apitoxin Versus Soft Laser for Management of Aphthous Ulceration

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 15 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The current study evaluated the clinical effect and outcome of locally applied bee venom versus low-level laser therapy (LLLT) for the treatment of recurrent aphthous ulceration.

Detailed description

Recurrent aphthous stomatitis (RAS) is a Painful, idiopathic, and recurrent inflammatory ulceration of the oral cavity. Despite their widespread use, prolonged or frequent application may result in adverse effects such as oral candida. In recent years, low-level laser therapy (LLLT) has gained attention as an alternative treatment for RAS. Apitoxin has been used traditionally to treat a variety of conditions, such as arthritis, rheumatism, back pain, cancer, and skin diseases.

Conditions

• Apitoxin
• Bee Venom Therapy
• Management
• Aphthous Ulceration

Interventions

Type	Name	Description
DEVICE	Low-level laser therapy (LLLT)	Patients managed by Low-level laser therapy (LLLT).
DRUG	Apitoxin	Patients managed with 0.3% Apitoxin Gel.

Timeline

• Start date: 2024-04-30
• Primary completion: 2025-02-02
• Completion: 2025-02-02
• First posted: 2025-08-22
• Last updated: 2025-08-22

Locations

1 site across 1 country: Egypt