NCT07134621

Target Organ Damage in Patients With Repaired Coarctation of Aorta and Exercise Induced Hypertension

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: University Medical Centre Ljubljana · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to obtain data on the effect of exercise induced hypertension on target organs in adult patients with repaired coarctation of the aorta. The main questions it aims to answer are: * patients with exercise induced hypertension have signs of hypertensive heart disease? * patients with exercise induced hypertension have increased arterial stiffness? * patients with exercise induced hypertension have signs of hypertensive renal damage? Participants will be invited for an outpatient appointment during which medical history and physical investigation will be performed. They will undergo cardiopulmonary exercise testing during which blood pressure will be measured regularly. Transthoracic echocardiography will also be performed as well as assessment of arterial stiffness by measuring pulse wave velocity. Renal function will be assessed by blood and urine analysis.

Conditions

• Coarctation of the Aorta

Timeline

• Start date: 2025-07-16
• Primary completion: 2026-02-01
• Completion: 2026-03-01
• First posted: 2025-08-21
• Last updated: 2025-09-02

Locations

1 site across 1 country: Slovenia