Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07131644

Sirolimus Discontinuation Strategies in Kaposiform Hemangioendothelioma

A Randomized Controlled Trial Comparing Three Sirolimus Discontinuation Strategies in Patients With Kaposiform Hemangioendothelioma

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
120 (estimated)
Sponsor
West China Hospital · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

Sirolimus has demonstrated efficacy in the treatment of kaposiform hemangioendothelioma (KHE); however, a high rate of rebound growth following discontinuation has been reported, highlighting the clinical importance of establishing an appropriate withdrawal regimen.

Conditions

Interventions

TypeNameDescription
DRUGSirolimusComparison of different sirolimus discontinuation strategies.

Timeline

Start date
2025-09-13
Primary completion
2027-09-01
Completion
2028-02-01
First posted
2025-08-20
Last updated
2025-09-08

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07131644. Inclusion in this directory is not an endorsement.