Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07130565

Pan-Amyloid PET/CT in Various Amyloid-Related Disease

Status
Recruiting
Phase
Study type
Observational
Enrollment
500 (estimated)
Sponsor
Tianjin Medical University · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Accepted

Summary

To evaluate the potential usefulness of 18F-92/AV45/TPZA/FT8, 11C-PIB positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Pan-Amyloid-related disease patients.

Detailed description

Subjects with various Pan-Amyloid-related disease patients underwent 18F-92/AV45TPZA/FT8, 11C-PIB PET/CT either for an initial assessment or for recurrence detection. Lesions uptake was quantified by the maximum standard uptake value (SUVmax). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of 18F-92/AV45TPZA/FT8, 11C-PIB PET/CT were calculated.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TEST18F-92/AV45/TPZA/FT8, 11CPIBEach subject receive a single intravenous injection of 18F-92/AV45/TPZA/FT8, 11C-PIB and undergo PET/CT or MRI imaging within the specificed time.

Timeline

Start date
2023-11-01
Primary completion
2028-11-01
Completion
2028-11-01
First posted
2025-08-19
Last updated
2025-08-19

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT07130565. Inclusion in this directory is not an endorsement.