NCT07129057

Effect of Mindfulness-Based Protocols on Psychological Parameters and Biological Markers in Populations Exposed to Conditions of Persistent Distress

Effect of Mindfulness-Based Protocols on Psychological Parameters and Biological Markers in Populations Exposed to Conditions of Persistent Distress: a Randomized Controlled Trial in Healthcare Workers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Azienda Unita Sanitaria Locale di Piacenza · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn if a Mindfulness-Based Stress Reduction (MBSR) training can improve the mental health and well-being of healthcare professionals (HCPs) exposed to prolonged severe stress conditions. The main questions it aims to answer are: * Does an 8-week MBSR training lower the cortisol levels of HCPs exposed to prolonged severe stress conditions? * Does an 8-week MBSR training modify the psychological condition of HCPs exposed to prolonged severe stress conditions? Researchers will compare an 8-week MBSR training to no-training to see if MBSR training works to improve the mental health and well-being of HCPs. Participants will: * Partecipate or not partecipate to the MBSR training for 8 weeks * Visit the clinic at baseline, after the 8-week intervention (T1), and at follow-up after 6 months for checkups and tests

Conditions

• Distress, Psychological

Interventions

Type	Name	Description
OTHER	MBSR program	The MBSR program lasts eight consecutive weeks (two months), with group sessions lasting two and a half hours each and an intensive 8-hour full-day practice session. At each session, the participants receive audio tracks for daily home practice.

Timeline

• Start date: 2020-10-10
• Primary completion: 2024-09-30
• Completion: 2024-09-30
• First posted: 2025-08-19
• Last updated: 2025-08-19

Locations

1 site across 1 country: Italy