NCT07127952

Correlations of the Microvascular Abnormalities on NVC (Nail Fold Video Capillaroscopy) and GAVE (Gastric Antral Vascular Ectasia) as Seen on EGD

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 95 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to determine whether a procedure called capillaroscopy can help distinguish patients who are diagnosed with GAVE (gastric antral vascular ectasia) with an autoimmune disease versus idiopathic/other conditions based on EGD findings.

Detailed description

The primary aim of this study is to define the prevalence and findings (as per quantification) of nail fold video capillaroscopy abnormalities in patients with GAVE. The secondary aim is to compare the findings of NVC and clinical presentation in patients with GAVE.

Conditions

• Gastric Antral Vascular Ectasia

Interventions

Type	Name	Description
DEVICE	Video Capillaroscopy	A non-invasive imaging technique used to assess capillary structure and morphology in the nailfold area, commonly used in evaluating microvascular changes associated with connective tissue diseases.

Timeline

• Start date: 2025-05-03
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2025-08-17
• Last updated: 2026-01-29

Locations

3 sites across 1 country: United States

Regulatory

• FDA-regulated device study