NCT07127614

Primary Tumor Depth of Invasion and Lymph Node Management in Oral Squamous Cell Carcinoma

The Relationship Between Primary Tumor Depth of Invasion and Neck Lymph Nodes Management in T1T2N0 Oral Cavity Squamous Cell Carcinomas

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 25 (estimated)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

To evaluate the diagnostic accuracy of preoperative MRI in the determination of the primary tumor depth of invasion (DOI) as a predictor factor in neck lymph nodes management in T1T2N0 oral cavity squamous cell carcinomas as compared to the pathological depth of invasion

Detailed description

A diagnostic accuracy study comparing preoperative MRI scans to pathological examination of the resected oral squamous cell carcinoma with lymph nodes to determine the depth of invasion.

Conditions

• Squamous Cell Carcinoma Mouth

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	MRI	pre-operative MRI scan
DIAGNOSTIC_TEST	Histo-Pathological examination of the resected tumor tissues	histo-pathological examination of the resected tumor tissues with the lymph nodes involved to determine the pathological depth of invasion

Timeline

• Start date: 2025-08-10
• Primary completion: 2026-01-01
• Completion: 2026-01-01
• First posted: 2025-08-17
• Last updated: 2025-08-17

Locations

1 site across 1 country: Egypt