NCT07127198

Tolerance and Appetite Reduction of a Nutritional Solution With Intragastric Gelation Properties

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The physical properties of a food product, such as its gelling properties in the stomach can influence how full a person may feel after its consumption. Decreasing appetite feeling through consumption of such a product with a low energy content may contribute to weight management. The study will assess if a drink with gelation properties in the stomach can reduce appetite and therefore contribute to weight management. This is a single-center, double-blinded, 4 arm cross-over randomized controlled study looking to enroll 24 adult participants. The study will be performed at the Clinical Innovation Lab (CIL), Nestlé Research, Lausanne. Enrolled participants will have 4 visit days after the screening visit. They will consume one of the test products, or control at each visit and complete the study assessments.

Conditions

• Weight Management

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Beverage Variant 1 (low gelation properties)	The first interventional product for this study is a drink containing protein and fiber at a concentration 1. It will come in a ready to drink format for the participants.
DIETARY_SUPPLEMENT	Beverage Variant 2 (medium gelation properties)	The first interventional product for this study is a drink containing protein and fiber at a concentration 2. It will come in a ready to drink format for the participants.
DIETARY_SUPPLEMENT	Beverage Variant 3 (high gelation properties)	The first interventional product for this study is a drink containing protein and fiber at a concentration 3. It will come in a ready to drink format for the participants.
OTHER	Control group (no gelation property)	The control product for this study is a drink containing protein and fiber. It will come in a ready to drink format for the participants.

Timeline

• Start date: 2025-05-22
• Primary completion: 2025-10-31
• Completion: 2025-10-31
• First posted: 2025-08-17
• Last updated: 2025-12-19

Locations

1 site across 1 country: Switzerland