NCT07126418

Sex-Based Differences in Cervical Joint Position Sense in Patients With Chronic Mechanical Neck Pain

Sex-Based Differences in Cervical Joint Position Sense and Disability in Patients With Chronic Mechanical Neck Pain: A Cross-Sectional Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This is across sectional observational study aims to investigate whether there are sex-based differences in cervical proprioception, pain intensity, and neck disability in patients with chronic mechanical neck pain. The findings may contribute to better individualized care plans and inform future clinical guidelines.

Detailed description

Neck pain is a common condition and one of the leading causes of disability worldwide, with mean estimates of 7.6% point prevalence (range, 5.9-38.7%), 37% annual prevalence (range, 16.7-75%), and 48.5% lifetime prevalence(range, 14.2-71%). Although neck pain can be attributed to traumatic (such as whiplash associated) disorders, metabolic, neoplastic, inflammatory, or infectious diseases, most neck pain has no discernable cause and is considered to be idiopathic. Chronic mechanical neck pain (CMNP) is a prevalent musculoskeletal condition, particularly among working-age adults, with a higher prevalence observed in females compared to males. The condition is commonly associated with impairments in cervical proprioception, pain, and functional disability. Cervical joint position sense (JPS) is a crucial component of sensorimotor control and has been found to be impaired in individuals with chronic neck pain. The clinical practice guidelines for chronic idiopathic neck pain do not support percutaneous or open surgical treatment and recommend conservative treatment. However, as conservative treatment usually fails to maintain long-term efficacy, clinical studies begin to pay attention to the evaluation and management of proprioceptive dysfunction in patients with idiopathic neck pain. Sex differences in pain perception and musculoskeletal disorders have been well-documented in the literature. A previous study revealed that the repositioning accuracy of the knee joint was significantly lower in female participants than in males and Sex-based difference in the accuracy of knee joint proprioception may imply that knee proprioceptive sensitivity might potentially contribute to the high incidence of knee injury in females compared with males. Another study showed that shoulder position sense, as part of the neuromuscular control system, differs between men and women. the findings showed a significant difference in constant position sense error between men and women and a significantly higher variability in the performance of men compared to women. However, limited studies have directly compared cervical proprioception between males and females in the context of chronic mechanical neck pain. Understanding these differences is essential for optimizing rehabilitation strategies and personalizing interventions. This study aims to investigate whether there are sex-based differences in cervical proprioception, pain intensity, and neck disability in patients with chronic mechanical neck pain. The findings may contribute to better individualized care plans and inform future clinical guidelines.

Conditions

• Chronic Mechanical Neck Pain

Interventions

Type	Name	Description
OTHER	observation (cervical proprioception, neck pain and neck disability)	1\) Assessment of cervical proprioception using CROM device: Head reposition accuracy tests: neutral head position (NHP) and target head position (THP) tests are common tests used to assess cervical proprioception. Repositioning to the NHP and repositioning into THP. The test procedures were the same as those described by Lee et al., 2006. The NHP test measures the subject's ability to actively reposition their head to their self-selected neutral position. The THP test measures the individual's ability to actively reposition the head to a previously demonstrated target position. A) Neutral head position: After explaining the testing procedure, the CROM device will securely fixed on the head of the subject. The participants will instructed to sit upright with their feet flat on the floor, their back against the chair backrest and facing straight ahead, this position will established as their self-selected "NHP". The magnetic part of the unit was then placed so that it was put

Timeline

• Start date: 2025-09-10
• Primary completion: 2026-02-01
• Completion: 2026-02-01
• First posted: 2025-08-17
• Last updated: 2026-02-06

Locations

1 site across 1 country: Egypt