Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT07125703

Observational Study With Additional Procedures: Metabolomic and Ultrastructural Findings of Allograft in Heart Transplantation and Their Correlation With Graft Dysfunction.

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
14 (actual)
Sponsor
Fondazione IRCCS Policlinico San Matteo di Pavia · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This is a single center retrospective/prospective observational study with additional procedures meant to evaluate molecular mechanisms underlying injury in donor's heart. The research project will focus on Metabolomics by NMR and LC-MS and ultrastructural analysis using electron microscopy of endomyocardial biopsies (EMB).In our clinical protocol of heart transplantation, myocardial biopsy samples are routinely provided at intraoperative and postoperative time.

Conditions

Timeline

Start date
2024-06-18
Primary completion
2025-12-31
Completion
2025-12-31
First posted
2025-08-15
Last updated
2025-08-15

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT07125703. Inclusion in this directory is not an endorsement.