NCT07125599

The Association Between Different Markers With Development of Maternal and Neonatal Complications in Women With Severe Preeclampsia

The Association Between Clinical, Laboratory and Ultrasonographic Findings With Development of Maternal and Neonatal Complications in Women With Severe Preeclampsia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 284 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

pregnant women diagnosed with severe preeclampsia were subjected to • Full history taking including a detailed history of the hypertension state during the current pregnancy (onset, course, current medication, and whether the blood pressure is controlled or not).gravidity , parity mode of delivery any medical disorders, the presence of headache ,blurring of vision and epigastric pain. * Complete physical examination: general (including BMI \& blood pressure measurement) and obstetric examinations. * Routine obstetric ultrasound and Doppler indices Including umbilical artery Doppler (RI). * Laboratory investigations : 1\. Complete blood count (CBC). 2 albuminuria will be detected by dipstick kits . 3. Liver enzymes \& kidney function. 4.PT,PC,INR. * Pelvic-Abdominal ultrasound to assess the presence of ascites Ultrasound examination will be performed by a consultant obstetrician to detect free fluid in the peritoneal cavity, especially at hepato-renal pouch, sub-splenic area, or para-colic gutters. The presence of ascites will be further confirmed at the time of delivery. 3-All labours will be attended by an expert neonatologist and the following will be recorded: * APGAR score at (1 min). * The further need for neonatal intensive care unit (NICU) admission. * Perinatal death

Detailed description

pregnant women diagnosed with severe preeclampsia were subjected to • Full history taking including a detailed history of the hypertension state during the current pregnancy (onset, course, current medication, and whether the blood pressure is controlled or not).gravidity , parity mode of delivery any medical disorders, the presence of headache ,blurring of vision and epigastric pain. * Complete physical examination: general (including BMI \& blood pressure measurement) and obstetric examinations. * Routine obstetric ultrasound and Doppler indices Including umbilical artery Doppler (RI). * Laboratory investigations : 1\. Complete blood count (CBC). 2 albuminuria will be detected by dipstick kits . 3. Liver enzymes \& kidney function. 4.PT,PC,INR. * Pelvic-Abdominal ultrasound to assess the presence of ascites Ultrasound examination will be performed by a consultant obstetrician to detect free fluid in the peritoneal cavity, especially at hepato-renal pouch, sub-splenic area, or para-colic gutters. The presence of ascites will be further confirmed at the time of delivery. 3-All labours will be attended by an expert neonatologist and the following will be recorded: * APGAR score at (1 min). * The further need for neonatal intensive care unit (NICU) admission. * Perinatal death

Conditions

• Severe Preeclampsia

Timeline

• Start date: 2020-05-02
• Primary completion: 2025-04-30
• Completion: 2025-05-20
• First posted: 2025-08-15
• Last updated: 2025-08-27

Locations

1 site across 1 country: Egypt