NCT07123428

Single and Multiple Ascending Doses and Food Effect Study of TRD205 in Healthy Volunteers

A Phase I Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of and Food Effect on TRD205 After Single and Multiple Doses in Healthy Adult Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 151 (actual)
• Sponsor: Beijing Tide Pharmaceutical Co., Ltd · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This is a Phase I clinical study to evaluate the safety, tolerability, and pharmacokinetics of TRD205 after single and multiple doses and to evaluate the effect of food on TRD205 in healthy adult subjects.

Detailed description

This study consists of three parts: * Single ascending dose study * Multiple ascending dose study * Food effect study

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	TRD205	TRD205 tablet
DRUG	Placebo	TRD205 placebo tablet

Timeline

• Start date: 2024-01-26
• Primary completion: 2024-11-27
• Completion: 2025-02-27
• First posted: 2025-08-14
• Last updated: 2025-08-14

Locations

1 site across 1 country: China