NCT07123402

To Evaluate the Efficacy and Safety of TRD205 Tablets in the Treatment of Chronic Postoperative Neuralgia

A Multicenter, Randomized, Double-blind, Placebo-controlled, Dose-finding Phase II Clinical Trial to Evaluate the Efficacy and Safety of TRD205 Tablets in the Treatment of Chronic Postoperative Neuralgia

• Status: Enrolling By Invitation
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 184 (estimated)
• Sponsor: Beijing Tide Pharmaceutical Co., Ltd · Industry
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is a phase II, multicenter ,randomized, double-blind, placebo-controlled, dose-finding study designed to evaluate the efficacy and safety of TRD205 tablets in the treatment of chronic postoperative neuralgia

Detailed description

This study used a placebo as a control to explore the efficacy, safety and pharmacokinetic characteristics of multiple administration of TRD205 tablets at different doses forchronic postoperative neuralgia .

Conditions

• Chronic Postoperative Neuralgia

Interventions

Type	Name	Description
DRUG	TRD205 tablets	orally ;Take TRD205 1 tablets and Placebo 2 tablets
DRUG	TRD205 tablets	orally ;Take TRD205 2 tablets and Placebo 1 tablets
DRUG	TRD205 tablets	orally ;Take TRD205 3 tablets and Placebo 0 tablets
DRUG	Placebo	orally ;Take Placebo 3 tablets

Timeline

• Start date: 2025-04-09
• Primary completion: 2026-04-20
• Completion: 2026-05-27
• First posted: 2025-08-14
• Last updated: 2025-08-17

Locations

1 site across 1 country: China