Trials / Active Not Recruiting
Active Not RecruitingNCT07122466
Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy
Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy in Patients With Advanced Pancreatic Cancer: a Prospective, Observational Pilot Study
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 24 (actual)
- Sponsor
- Northwell Health · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a study that aims to understand whether a blood test measuring tumor DNA circulating in the bloodstream (circulating tumor DNA; ctDNA) shows a similar response as observed by a follow-up CT scan. To study this question, ctDNA will be measured at the same times as CT scans (just before the start of treatment, as well as 2 months after), and the response measured by the ctDNA change will be compared to the response seen on the changes between the CT scans. The goal is to make sure that ctDNA response correlates well with CT scan response measurement.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Tumor DNA circulating in the bloodstream (circulating tumor DNA; ctDNA) | ctDNA will be measured at the same times as CT scans (just before the start of treatment, as well as 2 months after), and the response measured by the ctDNA change will be compared to the response seen on the changes between the CT scans. The goal is to make sure that ctDNA response correlates well with CT scan response measurement. |
Timeline
- Start date
- 2023-05-22
- Primary completion
- 2023-10-17
- Completion
- 2025-09-01
- First posted
- 2025-08-14
- Last updated
- 2025-08-14
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT07122466. Inclusion in this directory is not an endorsement.