NCT07119827

Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury

Neuropsychology and Personality: Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 250 (estimated)
• Sponsor: Universita di Verona · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke. The secondary aims are to assess the effects of premorbid personality on the sort- and long-term recovery in autonomy (disability), cognitive functions, psycho-behavioral functioning, motor skills, and social participation. Evaluate the incidence of premorbid personality alterations. Investigate personality changes 12-18 months after the neurological event.

Detailed description

Participants included in the study will undergo cognitive, motor, psychological, behavioral, personality, and disability assessments at different time points following the neurological event: T0: Initial assessment upon admission to the rehabilitation facility; within 90 days of the event for patients with severe acquired brain injury (sABI), as soon as cognitive evaluation becomes feasible (LCF ≥ 6); within 30 days of the event for stroke patients, as soon as cognitive assessment is possible. T1: At discharge from the inpatient rehabilitation program, provided that at least 30 days have passed since the initial assessment (T0). T2: At 12 months post-event for stroke patients and at 18 months post-event for patients with ABI.

Conditions

• Ictus
• Severe Acquired Brain Injury
• sABI

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Motor, cognitive and psychological assessment	Participants evaluated at T0 (Initial assessment upon admission to the rehabilitation facility), T1 (at discharge from the inpatient rehabilitation program, as long as at least 30 days have passed since the initial assessment (T0), T2 (at 12 months from the event for patients with stroke, and at 18 months from the event for patients with sABI).

Timeline

• Start date: 2025-05-01
• Primary completion: 2028-05-01
• Completion: 2028-05-01
• First posted: 2025-08-13
• Last updated: 2025-08-13

Locations

1 site across 1 country: Italy