NCT07118579

Effects of Remimazolam and Ciprofol TIVA on PRAE in Pediatric Tonsillectomy and Adenoidectomy

Effects of Remimazolam and Ciprofol Total Intravenous Anesthesia on Perioperative Respiratory Adverse Events in Pediatric Tonsillectomy and Adenoidectomy: A Randomized Controlled Study

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 114 (estimated)
• Sponsor: Tongji Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 12 Years
• Healthy volunteers: Not accepted

Summary

To observe the effects of remimazolam versus ciprofol TIVA on PRAE in pediatric tonsillectomy and adenoidectomy.

Detailed description

To observe the effects of remimazolam versus ciprofol TIVA on PRAE in pediatric tonsillectomy and adenoidectomy, aiming to enhance surgical safety and improve postoperative outcomes in pediatric patients.

Conditions

• Tonsillectomy With or Without Adenoidectomy

Interventions

Type	Name	Description
DRUG	Remimazolam	remimazolam induction (0.3-0.5 mg/kg) + maintenance (1-3 mg/kg/h)
DRUG	Propofol	Anesthesia induction (2-3 mg/kg) + Anesthesia maintenance (6-10 mg/kg/h)
DRUG	Ciprofol	Anesthesia induction (0.4-0.5 mg/kg) + Anesthesia maintenance (0.8-1.2 mg/kg/h)

Timeline

• Start date: 2025-09-23
• Primary completion: 2026-08-01
• Completion: 2026-08-01
• First posted: 2025-08-12
• Last updated: 2025-11-21

Locations

1 site across 1 country: China