NCT07116356

Molecular Characterization of Carbapenemase-Producing Enterobacterales

Molecular Characterization of Carbapenemase-Producing Enterobacterales Isolated From Clinical Samples in Egypt

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 4 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Bacterial infections with carbapenem resistant pathogens are one of the major threats in immunocompromised patients, especially among cancer patients .Furthermore, Gram negative pathogens are becoming increasingly prevalent and have become an ongoing global health concern .Emergence of Gram-negative pathogens, especially Enterobacterales that avert many of the human defense mechanisms are alarmingly increasing and most of these pathogens are resistant to many of the in-use antibiotics including carbapenems .

Conditions

• Acute Myeloid Leukemia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Antibiotic administration	different samples were collected from patients admitted at oncology center at sohag
DIAGNOSTIC_TEST	Molecular detection of antibiotic resistance	Molecular detection of carbapenem resistant genes: * Extraction of nucleic acid from isolated organisms by boiling. * Primers will be used for detection of carbaenem resistant genes

Timeline

• Start date: 2025-09-10
• Primary completion: 2025-09-30
• Completion: 2026-02-20
• First posted: 2025-08-11
• Last updated: 2025-08-11

Locations

1 site across 1 country: Egypt