NCT07113704

Fundus-First Laparoscopic Cholecystectomy in Difficult Gallbladders: A Safe Alternative Technique

Fundus-First Laparoscopic Cholecystectomy in Difficult Gallbladders: A Retrospective Cross-Sectional Study on a Safe Alternative to Avoid Conversion

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 124 (actual)
• Sponsor: KANAN ISMAYILZADA, MD · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This retrospective cross-sectional study evaluated the safety and effectiveness of the fundus-first laparoscopic cholecystectomy (FFLC) technique in patients with difficult gallbladders. A total of 124 patients who underwent FFLC between 2023 and 2024 were reviewed. The study assessed operative time, intraoperative complications, conversion rates, and postoperative outcomes. The results suggest that FFLC is a safe and feasible approach that can reduce the need for conversion to open surgery in complex cases. The study was conducted at a private hospital in Istanbul, Turkey

Detailed description

This retrospective study was conducted at a private healthcare institution without a formal IRB. All patient data were anonymised before analysis, and written informed consent was obtained from all patients for the academic use of their clinical data

Conditions

• Cholelithiasis

Interventions

Type	Name	Description
PROCEDURE	Conventional Laparoscopic Cholecystectomy	Standard laparoscopic cholecystectomy technique starting at Calot's triangle. Used as the comparator group in this study.
PROCEDURE	Fundus-First Laparoscopic Cholecystectomy	Laparoscopic cholecystectomy technique initiated at the gallbladder fundus and carried out retrogradely toward Calot's triangle. This method was applied to difficult gallbladders (Nassar Grade 3-4) to improve operative safety and avoid conversion to open surgery.

Timeline

• Start date: 2023-01-05
• Primary completion: 2024-04-01
• Completion: 2024-04-10
• First posted: 2025-08-11
• Last updated: 2025-08-11

Locations

1 site across 1 country: Turkey (Türkiye)