NCT07113457

Assessing Upper Extremity Function in Chronic Stroke Survivors Through Acute Intermittent Hypoxia

Assessing Upper Extremity Function in Chronic Stroke Survivors: Enhancing Neural Recovery With Acute Intermittent Hypoxia

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Shirley Ryan AbilityLab · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Here we aim to observe effects of acute intermittent hypoxia in persons who have experienced a single stroke. We have previously shown this technique to be safe and effective at increasing strength in persons with disabilities, and here are aiming to determine the mechanism of how the breathing method modulates motor function.

Detailed description

Here we aim to observe effects of acute intermittent hypoxia in persons who have experienced a single stroke. We have previously shown this technique to be safe and effective at increasing strength in persons with disabilities, and here are aiming to determine the mechanism of how the breathing method modulates motor function.

Conditions

• Stroke

Interventions

Type	Name	Description
OTHER	Acute Intermittent Hypoxia (AIH)	This intervention involves breathing lowered levels of oxygen (similar to those experienced on a tall mountain) for 60 seconds at a time. This is immediately followed by 60 seconds of breathing normal room air. These bouts are repeated approximately 15 times. For the intervention, the participant is fitted with a non-rebreathing mask which supplies the two different air levels

Timeline

• Start date: 2025-06-02
• Primary completion: 2026-08-01
• Completion: 2027-08-01
• First posted: 2025-08-08
• Last updated: 2026-03-20

Locations

1 site across 1 country: United States