NCT07112248

Effects of Soluble Fiber Supplements on Sperm Quality in Males With Obesity: a Randomized Trial

A Randomized Controlled Trial Investigating the Effects of Soluble Dietary Fiber Supplements on Sperm Quality Parameters in Males With Obesity

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Huazhong University of Science and Technology · Academic / Other
• Sex: Male
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Obesity-related poor sperm quality is a significant public health issue, acting as a major contributor to male infertility. Dietary intervention has emerged as an effective strategy to manage obesity and improve sperm quality. Soluble dietary fiber (SDF), an essential nutritional component, plays a crucial role in regulating host health. Notably, insufficient SDF intake has been associated with both obesity and low sperm motility. However, the effect of SDF supplementation on sperm quality in males with obesity remains unclear. Thus, we conducted a randomized, placebo-controlled study to investigate the effect of SDF supplementation on sperm quality in males with obesity.

Conditions

• Obesity-related Poor Sperm Quality
• Gut Microbiota

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo	Maltodextrin
DIETARY_SUPPLEMENT	inulin	Inulin is a kind of soluble dietary fiber.

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-12-31
• Completion: 2027-06-30
• First posted: 2025-08-08
• Last updated: 2025-08-08