NCT07111702

Prophylactic Antibiotics in Groin Hernioplasty

Prophylactic Antibiotics in Groin Hernioplasty: A Prospective Cohort Study on the Prevention of Surgical Site Infection

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Sana'a University · Academic / Other
• Sex: Male
• Age: 17 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The role of prophylactic antibiotics in preventing surgical site infections (SSI) for clean procedures like groin hernia repair remains controversial. This study aimed to evaluate the association between antibiotic prophylaxis and SSI rates in a real-world clinical setting and to identify independent risk factors for SSI. The study prospectively followed 100 male patients undergoing elective open groin hernioplasty. Patients were categorized based on the surgeon's decision into two groups: those who received a single dose of intravenous cefazolin (Antibiotic Group) and those who did not (No Antibiotic Group). The main outcome was the rate of SSI within 30 days of surgery.

Conditions

• Surgical Site Infection
• Groin Hernia
• Hernioplasty

Interventions

Type	Name	Description
DRUG	Cefazolin	A single 2g intravenous dose administered once before surgery.

Timeline

• Start date: 2023-10-01
• Primary completion: 2024-05-30
• Completion: 2024-05-30
• First posted: 2025-08-08
• Last updated: 2025-08-13

Locations

1 site across 1 country: Yemen