Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07110571

A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer

A Multi-cohort, Multi-center Phase II Clinical Study of Adebrelimab in Combination With SHR-A1811/SHR-A1904 and Chemotherapy or Adebrelimab in Combination With SHR-8068 as the Treatment in Subjects With Gastric or Gastroesophageal Junction Cancer

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
200 (estimated)
Sponsor
Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This is a multi-cohort, multi-center Phase II clinical study exploring the efficacy of treatment with either Adebrelimab plus SHR-A1811/SHR-A1904 and chemotherapy, or Adebrelimab plus SHR-8068 in patients with gastric or gastroesophageal junction (GEJ) cancer. The study also evaluates the safety and tolerability of these combination regimens.

Conditions

Interventions

TypeNameDescription
DRUGAdebrelimab InjectionAdebrelimab injection.
DRUGSHR-A1811 for InjectionSHR-A1811 for injection.
DRUGSHR-A1904 for InjectionSHR-A1904 for injection.
DRUGSHR-8068 InjectionSHR-8068 injection.

Timeline

Start date
2025-08-28
Primary completion
2026-08-01
Completion
2027-05-01
First posted
2025-08-07
Last updated
2026-01-09

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT07110571. Inclusion in this directory is not an endorsement.