NCT07109687

HIIT Versus MICT in COPD: Effects on Oxygenation, Pulmonary Function, and Strength

Comparison of the Effects of High-Intensity Interval Training and Moderate-Intensity Continuous Training on Peripheral and Respiratory Muscle Oxygenation, Pulmonary Function, Exercise Capacity, and Peripheral Muscle Strength in Individuals With Chronic Obstructive Pulmonary Disease

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Aynur Demirel · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition marked by airflow limitation and chronic inflammation, leading to reduced exercise capacity, peripheral muscle dysfunction, and dyspnea. High-Intensity Interval Training (HIIT) may offer a promising alternative for patients with low exercise tolerance; however, evidence on its effectiveness remains limited. This study aims to compare the effects of HIIT and Moderate-Intensity Continuous Training (MICT) on muscle oxygenation, pulmonary function, exercise capacity, and peripheral muscle strength in individuals with COPD. Participants will undergo an 8-week exercise program, twice weekly. HIIT will consist of 1-minute intervals at 90% and 30-40% of peak workload, while MICT will involve continuous cycling at 65% of peak workload. Outcomes will be assessed at baseline, week 4, and week 8. Data will be analyzed using SPSS. This study seeks to determine the more effective training modality to optimize COPD rehabilitation.

Conditions

• Chronic Obstructive Pulmonary Disease (COPD)

Interventions

Type	Name	Description
OTHER	HIIT GROUP	Participants will perform a 31-minute protocol on a cycle ergometer consisting of 1-minute high-intensity intervals at 90% of peak workload (W peak) and low-intensity intervals at 30-40% of W peak, twice a week for 8 weeks.
OTHER	MICT	Moderate intensity continous exercise

Timeline

• Start date: 2025-10-01
• Primary completion: 2027-03-01
• Completion: 2027-06-01
• First posted: 2025-08-07
• Last updated: 2025-08-07