NCT07109622

Effect of Herbal Supplement on Improving Sperm Virility

A Randomized, Double-blind, Placebo-controlled Pilot Study to Evaluate the Efficacy of LN18178 on Improving Sperm Virility (Sperm Motility, Sperm Concentration, and Sperm Morphology)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: GENCOR Lifestage Solutions · Academic / Other
• Sex: Male
• Age: 25 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the efficacy of LN18178 on improving sperm virility.

Detailed description

A total of 40 Males aged between 25-45 years will be included in the study. Assessment of inclusion and exclusion criteria will be done based on clinical and laboratory investigations. The eligible subjects will be randomized as per the computer-generated randomization list. The subjects will be assigned to either LN18178 - 400 mg or placebo arms at 1:1 ratio. The subjects will be instructed to take one capsule daily in the morning after breakfast for 12 weeks. A part from primary and secondary outcomes, the study will also record the vital signs and adverse events to evaluate the herbal composition safety and tolerability. The safety assessment of the LN18178 will also include routine laboratory investigations on blood, urine and clinical chemistry at screening and the final visit of the intervention.

Conditions

• Healthy Human Volunteers

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	LN18178	400 mg, One capsule to be consumed in the morning after breakfast for 12 weeks.
DIETARY_SUPPLEMENT	Placebo	One capsule to be consumed in the morning after breakfast for 12 Weeks

Timeline

• Start date: 2025-08-08
• Primary completion: 2026-02-10
• Completion: 2026-02-10
• First posted: 2025-08-07
• Last updated: 2025-08-07